TL;DR: Silandrone (CAS 5055-42-5) is a chemical compound with molecular formula C22H36O2Si and molecular weight 360.24844 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-17-trimethylsilyloxy-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Also Known As: Silandrone, Silandrona, Silandronum, O-Trimethylsilyltestosterone, Silandrone [USAN:INN]
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
| Molecular Formula | C22H36O2Si |
| Molecular Weight | 360.24844 g/mol |
| XLogP | 5.74 |
| Topological Polar Surface Area (TPSA) | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 360.24844 Da |
| Heavy Atoms | 25 |
| Complexity | 604.0 |
| SMILES | C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O[Si](C)(C)C)CCC4=CC(=O)CC[C@]34C |
| InChIKey | HNZDTAXZHUDITM-WLNPFYQQSA-N |
The XLogP value of 5.74 indicates that Silandrone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.3 Ų, Silandrone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Silandrone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
The CAS number of Silandrone is 5055-42-5.
The molecular formula of Silandrone is C22H36O2Si.
The molecular weight of Silandrone is 360.24844 g/mol.
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