Terfenadine
TL;DR: Terfenadine (CAS 50679-08-8) is a chemical compound with molecular formula C32H41NO2 and molecular weight 471.31372 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol
Also Known As: terfenadine, Seldane, Triludan, Ternadin, Teldane
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C32H41NO2 |
| Molecular Weight | 471.31372 g/mol |
| XLogP | 6.6 |
| Topological Polar Surface Area (TPSA) | 43.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 9 |
| Exact Mass | 471.31372 Da |
| Heavy Atoms | 35 |
| Complexity | 582.0 |
| Melting Point | 147 |
| Solubility | 0.0963 |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O |
| InChIKey | GUGOEEXESWIERI-UHFFFAOYSA-N |
Product Description
Applications: Terfenadine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Terfenadine is a pharmaceutical intermediate identified by CAS number 50679-08-8 and the molecular formula C32H41NO2 and a molecular weight of 471.31 g/mol. Physically, the compound has a solubility: 0.0963. Synonyms include terfenadine and Seldane.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Terfenadine
Property Insights of Terfenadine
The XLogP value of 6.6 indicates that Terfenadine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 43.7 Ų, Terfenadine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Terfenadine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Terfenadine?
The CAS number of Terfenadine is 50679-08-8.
What is the molecular formula of Terfenadine?
The molecular formula of Terfenadine is C32H41NO2.
What is the molecular weight of Terfenadine?
The molecular weight of Terfenadine is 471.31372 g/mol.
What are the applications of Terfenadine?
Terfenadine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Terfenadine?
You can request a quote for Terfenadine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Terfenadine?
Yes, CoreyChem provides custom synthesis services for Terfenadine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.