Ibudilast
TL;DR: Ibudilast (CAS 50847-11-5) is a chemical compound with molecular formula C14H18N2O and molecular weight 230.1419 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one
Also Known As: ibudilast, Ketas, Ibudilastum, Eyevinal, Ke Tas
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H18N2O |
| Molecular Weight | 230.1419 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 34.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 230.1419 Da |
| Heavy Atoms | 17 |
| Complexity | 288.0 |
| Solubility | 1.79e-01 g/L |
| SMILES | CC(C)C1=NN2C=CC=CC2=C1C(=O)C(C)C |
| InChIKey | ZJVFLBOZORBYFE-UHFFFAOYSA-N |
Product Description
Applications: Ibudilast is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Ibudilast is a pharmaceutical intermediate identified by CAS number 50847-11-5 and the molecular formula C14H18N2O and a molecular weight of 230.14 g/mol. Physically, the compound has a solubility: 1.79e-01 g/L. Synonyms include ibudilast and Ketas.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Ibudilast
Property Insights of Ibudilast
The XLogP value of 3.0 indicates that Ibudilast is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 34.4 Ų, Ibudilast exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Ibudilast has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Ibudilast?
The CAS number of Ibudilast is 50847-11-5.
What is the molecular formula of Ibudilast?
The molecular formula of Ibudilast is C14H18N2O.
What is the molecular weight of Ibudilast?
The molecular weight of Ibudilast is 230.1419 g/mol.
What are the applications of Ibudilast?
Ibudilast is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Ibudilast?
You can request a quote for Ibudilast directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Ibudilast?
Yes, CoreyChem provides custom synthesis services for Ibudilast and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.