Etofylline
TL;DR: Etofylline (CAS 519-37-9) is a chemical compound with molecular formula C9H12N4O3 and molecular weight 224.09094 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-(2-hydroxyethyl)-1,3-dimethylpurine-2,6-dione
Also Known As: Aethophyllinum, Frekaphyllin, Soluphylline, Cordalin, Phyllocormin N
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H12N4O3 |
| Molecular Weight | 224.09094 g/mol |
| XLogP | -1.2 |
| Topological Polar Surface Area (TPSA) | 78.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 224.09094 Da |
| Heavy Atoms | 16 |
| Complexity | 322.0 |
| Solubility | >33.6 [ug/mL] (The mean of the results at pH 7.4) |
| SMILES | CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CCO |
| InChIKey | NWPRCRWQMGIBOT-UHFFFAOYSA-N |
Product Description
Applications: Etofylline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Etofylline (CAS 519-37-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Etofylline (CAS 519-37-9) has the molecular formula C9H12N4O3 and a molecular weight of 224.09 g/mol. Reported properties include a solubility: >33.6 [ug/mL] (The mean of the results at pH 7.4). It is also known as Aethophyllinum and Frekaphyllin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Etofylline
Property Insights of Etofylline
The XLogP value of -1.2 indicates that Etofylline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Etofylline. Following Lipinski's Rule of Five, Etofylline has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Etofylline?
The CAS number of Etofylline is 519-37-9.
What is the molecular formula of Etofylline?
The molecular formula of Etofylline is C9H12N4O3.
What is the molecular weight of Etofylline?
The molecular weight of Etofylline is 224.09094 g/mol.
What are the applications of Etofylline?
Etofylline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Etofylline (CAS 519-37-9) with custom...
Where can I buy Etofylline?
You can request a quote for Etofylline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Etofylline?
Yes, CoreyChem provides custom synthesis services for Etofylline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.