N-Hydroxyphthalimide
TL;DR: N-Hydroxyphthalimide (CAS 524-38-9) is a chemical compound with molecular formula C8H5NO3 and molecular weight 163.02695 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-hydroxyisoindole-1,3-dione
Also Known As: N-HYDROXYPHTHALIMIDE, 2-hydroxyisoindoline-1,3-dione, 2-Hydroxyphthalimide, Phthaloxime, NHPI
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H5NO3 |
| Molecular Weight | 163.02695 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 57.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 163.02695 Da |
| Heavy Atoms | 12 |
| Complexity | 214.0 |
| Purity | 97% |
| Melting Point | 233.0 |
| SMILES | C1=CC=C2C(=C1)C(=O)N(C2=O)O |
| InChIKey | CFMZSMGAMPBRBE-UHFFFAOYSA-N |
Product Description
Applications: N-Hydroxyphthalimide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at 97%. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
N-Hydroxyphthalimide (CAS 524-38-9) is a heterocyclic building block with the molecular formula C8H5NO3 and a molecular weight of 163.03 g/mol. Synonyms include N-HYDROXYPHTHALIMIDE and 2-hydroxyisoindoline-1,3-dione.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H53704, H53704, H53704-5G , H53704-100G , H53704-500G , H53704-5G, H53704, H40807, H11696, H022
Chemical Property Profile of N-Hydroxyphthalimide
Property Insights of N-Hydroxyphthalimide
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-Hydroxyphthalimide. With a topological polar surface area (TPSA) of 57.6 Ų, N-Hydroxyphthalimide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-Hydroxyphthalimide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-Hydroxyphthalimide?
The CAS number of N-Hydroxyphthalimide is 524-38-9.
What is the molecular formula of N-Hydroxyphthalimide?
The molecular formula of N-Hydroxyphthalimide is C8H5NO3.
What is the molecular weight of N-Hydroxyphthalimide?
The molecular weight of N-Hydroxyphthalimide is 163.02695 g/mol.
What are the applications of N-Hydroxyphthalimide?
N-Hydroxyphthalimide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at 97%....
Where can I buy N-Hydroxyphthalimide?
You can request a quote for N-Hydroxyphthalimide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-Hydroxyphthalimide?
Yes, CoreyChem provides custom synthesis services for N-Hydroxyphthalimide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.