Tetrahydrocortisol
TL;DR: Tetrahydrocortisol (CAS 53-02-1) is a chemical compound with molecular formula C21H34O5 and molecular weight 366.24063 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-hydroxy-1-[(3R,5R,8S,9S,10S,11S,13S,14S,17R)-3,11,17-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone
Also Known As: TETRAHYDROCORTISOL, Urocortisol, Tetrahydro F, Tetrahydrocompound F, Tetrahydrohydrocortisone
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H34O5 |
| Molecular Weight | 366.24063 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 98.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 366.24063 Da |
| Heavy Atoms | 26 |
| Complexity | 593.0 |
| SMILES | C[C@]12CC[C@H](C[C@H]1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O)O |
| InChIKey | AODPIQQILQLWGS-GXBDJPPSSA-N |
Product Description
Applications: Tetrahydrocortisol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Tetrahydrocortisol (CAS 53-02-1) has the molecular formula C21H34O5 and a molecular weight of 366.24 g/mol. Synonyms include TETRAHYDROCORTISOL and Urocortisol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tetrahydrocortisol
Property Insights of Tetrahydrocortisol
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tetrahydrocortisol. The TPSA of 98.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Tetrahydrocortisol. Following Lipinski's Rule of Five, Tetrahydrocortisol has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tetrahydrocortisol?
The CAS number of Tetrahydrocortisol is 53-02-1.
What is the molecular formula of Tetrahydrocortisol?
The molecular formula of Tetrahydrocortisol is C21H34O5.
What is the molecular weight of Tetrahydrocortisol?
The molecular weight of Tetrahydrocortisol is 366.24063 g/mol.
What are the applications of Tetrahydrocortisol?
Tetrahydrocortisol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Tetrahydrocortisol?
You can request a quote for Tetrahydrocortisol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tetrahydrocortisol?
Yes, CoreyChem provides custom synthesis services for Tetrahydrocortisol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.