Tetrahydrocortisone
TL;DR: Tetrahydrocortisone (CAS 53-05-4) is a chemical compound with molecular formula C21H32O5 and molecular weight 364.22498 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
Also Known As: TETRAHYDROCORTISONE, Urocortisone, Tetrahydro E, Tetrahydro Cortisone, Tetrahydrocompound E
Application Areas
Top 5 of 8 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H32O5 |
| Molecular Weight | 364.22498 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 94.8 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 364.22498 Da |
| Heavy Atoms | 26 |
| Complexity | 632.0 |
| SMILES | C[C@]12CC[C@H](C[C@H]1CC[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O |
| InChIKey | SYGWGHVTLUBCEM-ZIZPXRJBSA-N |
Product Description
Applications: Tetrahydrocortisone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Tetrahydrocortisone is a pharmaceutical intermediate identified by CAS number 53-05-4 and the molecular formula C21H32O5 and a molecular weight of 364.22 g/mol. Synonyms include TETRAHYDROCORTISONE and Urocortisone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tetrahydrocortisone
Property Insights of Tetrahydrocortisone
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tetrahydrocortisone. The TPSA of 94.8 Ų falls within the moderate polarity range, balancing permeability and solubility for Tetrahydrocortisone. Following Lipinski's Rule of Five, Tetrahydrocortisone has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tetrahydrocortisone?
The CAS number of Tetrahydrocortisone is 53-05-4.
What is the molecular formula of Tetrahydrocortisone?
The molecular formula of Tetrahydrocortisone is C21H32O5.
What is the molecular weight of Tetrahydrocortisone?
The molecular weight of Tetrahydrocortisone is 364.22498 g/mol.
What are the applications of Tetrahydrocortisone?
Tetrahydrocortisone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg...
Where can I buy Tetrahydrocortisone?
You can request a quote for Tetrahydrocortisone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tetrahydrocortisone?
Yes, CoreyChem provides custom synthesis services for Tetrahydrocortisone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.