Nisoxetine
TL;DR: Nisoxetine (CAS 53179-07-0) is a chemical compound with molecular formula C17H21NO2 and molecular weight 271.15723 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine
Also Known As: Nisoxetine, Nisoxetina, Nisoxetinum, Compound 89218, Nisoxetine HCl
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H21NO2 |
| Molecular Weight | 271.15723 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 30.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 7 |
| Exact Mass | 271.15723 Da |
| Heavy Atoms | 20 |
| Complexity | 253.0 |
| SMILES | CNCCC(C1=CC=CC=C1)OC2=CC=CC=C2OC |
| InChIKey | ITJNARMNRKSWTA-UHFFFAOYSA-N |
Product Description
Applications: Nisoxetine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nisoxetine (CAS 53179-07-0) is a pharmaceutical intermediate with the molecular formula C17H21NO2 and a molecular weight of 271.16 g/mol. Synonyms include Nisoxetine and Nisoxetina.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nisoxetine
Property Insights of Nisoxetine
The XLogP value of 3.1 indicates that Nisoxetine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 30.5 Ų, Nisoxetine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nisoxetine has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nisoxetine?
The CAS number of Nisoxetine is 53179-07-0.
What is the molecular formula of Nisoxetine?
The molecular formula of Nisoxetine is C17H21NO2.
What is the molecular weight of Nisoxetine?
The molecular weight of Nisoxetine is 271.15723 g/mol.
What are the applications of Nisoxetine?
Nisoxetine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nisoxetine?
You can request a quote for Nisoxetine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nisoxetine?
Yes, CoreyChem provides custom synthesis services for Nisoxetine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.