Norfenefrine
TL;DR: Norfenefrine (CAS 536-21-0) is a chemical compound with molecular formula C8H11NO2 and molecular weight 153.07898 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(2-amino-1-hydroxyethyl)phenol
Also Known As: Norfenefrine, Norphenylephrine, Norphenephrine, Metacardiol, m-Octopamine
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.07898 g/mol |
| XLogP | -0.8 |
| Topological Polar Surface Area (TPSA) | 66.5 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 153.07898 Da |
| Heavy Atoms | 11 |
| Complexity | 119.0 |
| SMILES | C1=CC(=CC(=C1)O)C(CN)O |
| InChIKey | LRCXRAABFLIVAI-UHFFFAOYSA-N |
Product Description
Applications: Norfenefrine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Norfenefrine (CAS 536-21-0) has the molecular formula C8H11NO2 and a molecular weight of 153.08 g/mol. Synonyms include Norfenefrine and Norphenylephrine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Norfenefrine
Property Insights of Norfenefrine
The XLogP value of -0.8 indicates that Norfenefrine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 66.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Norfenefrine. Following Lipinski's Rule of Five, Norfenefrine has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Norfenefrine?
The CAS number of Norfenefrine is 536-21-0.
What is the molecular formula of Norfenefrine?
The molecular formula of Norfenefrine is C8H11NO2.
What is the molecular weight of Norfenefrine?
The molecular weight of Norfenefrine is 153.07898 g/mol.
What are the applications of Norfenefrine?
Norfenefrine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Norfenefrine?
You can request a quote for Norfenefrine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Norfenefrine?
Yes, CoreyChem provides custom synthesis services for Norfenefrine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.