Isoniazid
TL;DR: Isoniazid (CAS 54-85-3) is a chemical compound with molecular formula C6H7N3O and molecular weight 137.05891 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
pyridine-4-carbohydrazide
Also Known As: isoniazid, Isonicotinic acid hydrazide, Isonicotinohydrazide, Isoniazide, Rimifon
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H7N3O |
| Molecular Weight | 137.05891 g/mol |
| XLogP | -0.7 |
| Topological Polar Surface Area (TPSA) | 68.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 137.05891 Da |
| Heavy Atoms | 10 |
| Complexity | 120.0 |
| Melting Point | 340.5 °F (NTP, 1992) |
| Flash Point | 374 °F (NTP, 1992) |
| Vapor Pressure | Negligible (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 77 °F (NTP, 1992) |
| SMILES | C1=CN=CC=C1C(=O)NN |
| InChIKey | QRXWMOHMRWLFEY-UHFFFAOYSA-N |
Product Description
Applications: Isoniazid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Isoniazid (CAS 54-85-3) has the molecular formula C6H7N3O and a molecular weight of 137.06 g/mol. Reported properties include a solubility: greater than or equal to 100 mg/mL at 77 °F (NTP, 1992). Synonyms include isoniazid and Isonicotinic acid hydrazide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Isoniazid
Property Insights of Isoniazid
The XLogP value of -0.7 indicates that Isoniazid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 68.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Isoniazid. Following Lipinski's Rule of Five, Isoniazid has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Isoniazid?
The CAS number of Isoniazid is 54-85-3.
What is the molecular formula of Isoniazid?
The molecular formula of Isoniazid is C6H7N3O.
What is the molecular weight of Isoniazid?
The molecular weight of Isoniazid is 137.05891 g/mol.
What are the applications of Isoniazid?
Isoniazid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Isoniazid?
You can request a quote for Isoniazid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Isoniazid?
Yes, CoreyChem provides custom synthesis services for Isoniazid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.