Propafenone
TL;DR: Propafenone (CAS 54063-53-5) is a chemical compound with molecular formula C21H27NO3 and molecular weight 341.1991 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one
Also Known As: propafenone, Propafenona, Rythmol, Propafenonum, (R)-Propafenone
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H27NO3 |
| Molecular Weight | 341.1991 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 58.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 11 |
| Exact Mass | 341.1991 Da |
| Heavy Atoms | 25 |
| Complexity | 368.0 |
| Solubility | Slightly soluble |
| SMILES | CCCNCC(COC1=CC=CC=C1C(=O)CCC2=CC=CC=C2)O |
| InChIKey | JWHAUXFOSRPERK-UHFFFAOYSA-N |
Product Description
Applications: Propafenone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Propafenone (CAS 54063-53-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Propafenone is a pharmaceutical intermediate identified by CAS number 54063-53-5 and the molecular formula C21H27NO3 and a molecular weight of 341.2 g/mol. Physically, the compound has a solubility: Slightly soluble. It is also known as propafenone and Propafenona.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Propafenone
Property Insights of Propafenone
The XLogP value of 3.3 indicates that Propafenone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 58.6 Ų, Propafenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Propafenone has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Propafenone?
The CAS number of Propafenone is 54063-53-5.
What is the molecular formula of Propafenone?
The molecular formula of Propafenone is C21H27NO3.
What is the molecular weight of Propafenone?
The molecular weight of Propafenone is 341.1991 g/mol.
What are the applications of Propafenone?
Propafenone is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Propafenone (CAS 54063-53-5) with custom synthesis available from...
Where can I buy Propafenone?
You can request a quote for Propafenone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Propafenone?
Yes, CoreyChem provides custom synthesis services for Propafenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.