Nicardipine
TL;DR: Nicardipine (CAS 55985-32-5) is a chemical compound with molecular formula C26H29N3O6 and molecular weight 479.20563 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nicardipine, Nicardipinum, Nicardipino, Perpidine, Cardene
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C26H29N3O6 |
| Molecular Weight | 479.20563 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 114.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 10 |
| Exact Mass | 479.20563 Da |
| Heavy Atoms | 35 |
| Complexity | 856.0 |
| Melting Point | 136-138 °C |
| Solubility | 2.2 |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC |
| InChIKey | ZBBHBTPTTSWHBA-UHFFFAOYSA-N |
Product Description
Applications: Nicardipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nicardipine (CAS 55985-32-5) is a pharmaceutical intermediate with the molecular formula C26H29N3O6 and a molecular weight of 479.21 g/mol. Key physical properties include a solubility: 2.2. Synonyms include nicardipine and Nicardipinum.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nicardipine
Property Insights of Nicardipine
The XLogP value of 3.8 indicates that Nicardipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 114.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nicardipine. Following Lipinski's Rule of Five, Nicardipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nicardipine?
The CAS number of Nicardipine is 55985-32-5.
What is the molecular formula of Nicardipine?
The molecular formula of Nicardipine is C26H29N3O6.
What is the molecular weight of Nicardipine?
The molecular weight of Nicardipine is 479.20563 g/mol.
What are the applications of Nicardipine?
Nicardipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nicardipine?
You can request a quote for Nicardipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nicardipine?
Yes, CoreyChem provides custom synthesis services for Nicardipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.