Beta-Propiolactone
TL;DR: Beta-Propiolactone (CAS 57-57-8) is a chemical compound with molecular formula C3H4O2 and molecular weight 72.021126 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
oxetan-2-one
Also Known As: beta-propiolactone, Propiolactone, 2-Oxetanone, Oxetan-2-one, Betaprone
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C3H4O2 |
| Molecular Weight | 72.021126 g/mol |
| XLogP | -0.2 |
| Topological Polar Surface Area (TPSA) | 26.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 72.021126 Da |
| Heavy Atoms | 5 |
| Complexity | 57.0 |
| Melting Point | -27 °F (EPA, 1998) |
| Boiling Point | 324 °F at 760 mmHg decomposes (EPA, 1998) |
| Density | 1.146 at 68 °F (EPA, 1998) - Denser than water; will sink |
| Flash Point | 158 °F (EPA, 1998) |
| Vapor Pressure | 3.4 mmHg at 77 °F (EPA, 1998) |
| Refractive Index | INDEX OF REFRACTION: 1.413 @ 20 °C/D; 1.4110 @ 25 °C |
| Solubility | 10 to 50 mg/mL at 66 °F (NTP, 1992) |
| SMILES | C1COC1=O |
| InChIKey | VEZXCJBBBCKRPI-UHFFFAOYSA-N |
Product Description
Applications: Beta-Propiolactone is used in polymer chemistry and functional materials synthesis, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A polymer intermediate supplied by CoreyChem, Beta-Propiolactone (CAS 57-57-8) has the molecular formula C3H4O2 and a molecular weight of 72.02 g/mol. Reported properties include a density of 1.146 at 68 °F (EPA, 1998) - Denser than water; will sink g/cm³, a solubility: 10 to 50 mg/mL at 66 °F (NTP, 1992). Synonyms include beta-propiolactone and Propiolactone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Beta-Propiolactone
Property Insights of Beta-Propiolactone
The XLogP value of -0.2 indicates that Beta-Propiolactone is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 26.3 Ų, Beta-Propiolactone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Beta-Propiolactone has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Beta-Propiolactone?
The CAS number of Beta-Propiolactone is 57-57-8.
What is the molecular formula of Beta-Propiolactone?
The molecular formula of Beta-Propiolactone is C3H4O2.
What is the molecular weight of Beta-Propiolactone?
The molecular weight of Beta-Propiolactone is 72.021126 g/mol.
What are the applications of Beta-Propiolactone?
Beta-Propiolactone is used in polymer chemistry and functional materials synthesis, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project...
Where can I buy Beta-Propiolactone?
You can request a quote for Beta-Propiolactone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Beta-Propiolactone?
Yes, CoreyChem provides custom synthesis services for Beta-Propiolactone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.