3-(4-Dimethylaminobenzylidenyl)-2-indolinone
TL;DR: 3-(4-Dimethylaminobenzylidenyl)-2-indolinone (CAS 5812-07-7) is a chemical compound with molecular formula C17H16N2O and molecular weight 264.12625 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[[4-(dimethylamino)phenyl]methylidene]-1H-indol-2-one
Also Known As: dmbi, Enzastaurin, DMBI, indolinone, SU 4312, 3-(4-dimethylamino-benzylidenyl)-2-indolinone
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H16N2O |
| Molecular Weight | 264.12625 g/mol |
| XLogP | 3.0 |
| Topological Polar Surface Area (TPSA) | 32.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 264.12625 Da |
| Heavy Atoms | 20 |
| Complexity | 394.0 |
| SMILES | CN(C)C1=CC=C(C=C1)C=C2C3=CC=CC=C3NC2=O |
| InChIKey | UAKWLVYMKBWHMX-UHFFFAOYSA-N |
Product Description
Applications: 3-(4-Dimethylaminobenzylidenyl)-2-indolinone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 3-(4-Dimethylaminobenzylidenyl)-2-indolinone (CAS 5812-07-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
3-(4-Dimethylaminobenzylidenyl)-2-indolinone (CAS 5812-07-7) is a pharmaceutical intermediate with the molecular formula C17H16N2O and a molecular weight of 264.13 g/mol. It is also known as dmbi and Enzastaurin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone
Property Insights of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone
The XLogP value of 3.0 indicates that 3-(4-Dimethylaminobenzylidenyl)-2-indolinone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.3 Ų, 3-(4-Dimethylaminobenzylidenyl)-2-indolinone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-(4-Dimethylaminobenzylidenyl)-2-indolinone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone?
The CAS number of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone is 5812-07-7.
What is the molecular formula of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone?
The molecular formula of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone is C17H16N2O.
What is the molecular weight of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone?
The molecular weight of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone is 264.12625 g/mol.
What are the applications of 3-(4-Dimethylaminobenzylidenyl)-2-indolinone?
3-(4-Dimethylaminobenzylidenyl)-2-indolinone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies...
Where can I buy 3-(4-Dimethylaminobenzylidenyl)-2-indolinone?
You can request a quote for 3-(4-Dimethylaminobenzylidenyl)-2-indolinone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-(4-Dimethylaminobenzylidenyl)-2-indolinone?
Yes, CoreyChem provides custom synthesis services for 3-(4-Dimethylaminobenzylidenyl)-2-indolinone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.