N,N-Diethylnicotinamide
TL;DR: N,N-Diethylnicotinamide (CAS 59-26-7) is a chemical compound with molecular formula C10H14N2O and molecular weight 178.11061 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N,N-diethylpyridine-3-carboxamide
Also Known As: Nikethamide, N,N-DIETHYLNICOTINAMIDE, Nicethamide, Nikethyl, Anacardone
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H14N2O |
| Molecular Weight | 178.11061 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 33.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 178.11061 Da |
| Heavy Atoms | 13 |
| Complexity | 166.0 |
| Melting Point | 75 to 79 °F (NTP, 1992) |
| Boiling Point | 565 to 572 °F at 760 mmHg (some decomposition) (NTP, 1992) |
| Density | 1.058 to 1.066 at 77 °F (NTP, 1992) |
| Flash Point | 235 °F (NTP, 1992) |
| Solubility | greater than or equal to 100 mg/mL at 73 °F (NTP, 1992) |
| SMILES | CCN(CC)C(=O)C1=CN=CC=C1 |
| InChIKey | NCYVXEGFNDZQCU-UHFFFAOYSA-N |
Product Description
Applications: N,N-Diethylnicotinamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N,N-Diethylnicotinamide (CAS 59-26-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
N,N-Diethylnicotinamide (CAS 59-26-7) is a pharmaceutical intermediate with the molecular formula C10H14N2O and a molecular weight of 178.11 g/mol. Key physical properties include a density of 1.058 to 1.066 at 77 °F (NTP, 1992) g/cm³, a solubility: greater than or equal to 100 mg/mL at 73 °F (NTP, 1992). It is also known as Nikethamide and N,N-DIETHYLNICOTINAMIDE.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N,N-Diethylnicotinamide
Property Insights of N,N-Diethylnicotinamide
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N,N-Diethylnicotinamide. With a topological polar surface area (TPSA) of 33.2 Ų, N,N-Diethylnicotinamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N,N-Diethylnicotinamide has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N,N-Diethylnicotinamide?
The CAS number of N,N-Diethylnicotinamide is 59-26-7.
What is the molecular formula of N,N-Diethylnicotinamide?
The molecular formula of N,N-Diethylnicotinamide is C10H14N2O.
What is the molecular weight of N,N-Diethylnicotinamide?
The molecular weight of N,N-Diethylnicotinamide is 178.11061 g/mol.
What are the applications of N,N-Diethylnicotinamide?
N,N-Diethylnicotinamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies N,N-Diethylnicotinamide (CAS...
Where can I buy N,N-Diethylnicotinamide?
You can request a quote for N,N-Diethylnicotinamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N,N-Diethylnicotinamide?
Yes, CoreyChem provides custom synthesis services for N,N-Diethylnicotinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.