2-Hydroxyquinoline
TL;DR: 2-Hydroxyquinoline (CAS 59-31-4) is a chemical compound with molecular formula C9H7NO and molecular weight 145.05276 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1H-quinolin-2-one
Also Known As: 2-Hydroxyquinoline, 2-Quinolinol, Quinolin-2-ol, Carbostyril, 2-Quinolone
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H7NO |
| Molecular Weight | 145.05276 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 145.05276 Da |
| Heavy Atoms | 11 |
| Complexity | 198.0 |
| SMILES | C1=CC=C2C(=C1)C=CC(=O)N2 |
| InChIKey | LISFMEBWQUVKPJ-UHFFFAOYSA-N |
Product Description
Applications: 2-Hydroxyquinoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
2-Hydroxyquinoline is a pharmaceutical intermediate identified by CAS number 59-31-4 and the molecular formula C9H7NO and a molecular weight of 145.05 g/mol. Synonyms include 2-Hydroxyquinoline and 2-Quinolinol.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 2-Hydroxyquinoline
Property Insights of 2-Hydroxyquinoline
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Hydroxyquinoline. With a topological polar surface area (TPSA) of 29.1 Ų, 2-Hydroxyquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Hydroxyquinoline has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Hydroxyquinoline?
The CAS number of 2-Hydroxyquinoline is 59-31-4.
What is the molecular formula of 2-Hydroxyquinoline?
The molecular formula of 2-Hydroxyquinoline is C9H7NO.
What is the molecular weight of 2-Hydroxyquinoline?
The molecular weight of 2-Hydroxyquinoline is 145.05276 g/mol.
What are the applications of 2-Hydroxyquinoline?
2-Hydroxyquinoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 2-Hydroxyquinoline?
You can request a quote for 2-Hydroxyquinoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Hydroxyquinoline?
Yes, CoreyChem provides custom synthesis services for 2-Hydroxyquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.