Neostigmine
TL;DR: Neostigmine (CAS 59-99-4) is a chemical compound with molecular formula C12H19N2O2+ and molecular weight 223.14465 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[3-(dimethylcarbamoyloxy)phenyl]-trimethylazanium
Also Known As: NEOSTIGMINE, Eustigmine, Eustigmin, Vagostigmine, Prostigmine
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H19N2O2+ |
| Molecular Weight | 223.14465 g/mol |
| XLogP | 1.5 |
| Topological Polar Surface Area (TPSA) | 29.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 223.14465 Da |
| Heavy Atoms | 16 |
| Complexity | 246.0 |
| Solubility | 6.77e-02 g/L |
| SMILES | CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C |
| InChIKey | ALWKGYPQUAPLQC-UHFFFAOYSA-N |
Product Description
Applications: Neostigmine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Neostigmine (CAS 59-99-4) has the molecular formula C12H19N2O2+ and a molecular weight of 223.14 g/mol. Reported properties include a solubility: 6.77e-02 g/L. Synonyms include NEOSTIGMINE and Eustigmine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Neostigmine
Property Insights of Neostigmine
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Neostigmine. With a topological polar surface area (TPSA) of 29.5 Ų, Neostigmine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Neostigmine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Neostigmine?
The CAS number of Neostigmine is 59-99-4.
What is the molecular formula of Neostigmine?
The molecular formula of Neostigmine is C12H19N2O2+.
What is the molecular weight of Neostigmine?
The molecular weight of Neostigmine is 223.14465 g/mol.
What are the applications of Neostigmine?
Neostigmine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Neostigmine?
You can request a quote for Neostigmine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Neostigmine?
Yes, CoreyChem provides custom synthesis services for Neostigmine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.