Phloretin
TL;DR: Phloretin (CAS 60-82-2) is a chemical compound with molecular formula C15H14O5 and molecular weight 274.08414 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one
Also Known As: phloretin, Dihydronaringenin, Phloretol, 3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one, Asebogenol
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H14O5 |
| Molecular Weight | 274.08414 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 98.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 274.08414 Da |
| Heavy Atoms | 20 |
| Complexity | 312.0 |
| Melting Point | 263.5 °C |
| Solubility | 0.123 mg/mL at 16 °C |
| SMILES | C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O |
| InChIKey | VGEREEWJJVICBM-UHFFFAOYSA-N |
Product Description
Applications: Phloretin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Phloretin (CAS 60-82-2) has the molecular formula C15H14O5 and a molecular weight of 274.08 g/mol. Reported properties include a solubility: 0.123 mg/mL at 16 °C. Synonyms include phloretin and Dihydronaringenin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Phloretin
Property Insights of Phloretin
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Phloretin. The TPSA of 98.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Phloretin. Following Lipinski's Rule of Five, Phloretin has 4 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Phloretin?
The CAS number of Phloretin is 60-82-2.
What is the molecular formula of Phloretin?
The molecular formula of Phloretin is C15H14O5.
What is the molecular weight of Phloretin?
The molecular weight of Phloretin is 274.08414 g/mol.
What are the applications of Phloretin?
Phloretin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Phloretin?
You can request a quote for Phloretin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Phloretin?
Yes, CoreyChem provides custom synthesis services for Phloretin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.