N-Hydroxysuccinimide
TL;DR: N-Hydroxysuccinimide (CAS 6066-82-6) is a chemical compound with molecular formula C4H5NO3 and molecular weight 115.02694 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-hydroxypyrrolidine-2,5-dione
Also Known As: N-Hydroxysuccinimide, 1-hydroxypyrrolidine-2,5-dione, HOSu, Hydroxysuccinimide, 1-Hydroxysuccinimide
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C4H5NO3 |
| Molecular Weight | 115.02694 g/mol |
| XLogP | -1.4 |
| Topological Polar Surface Area (TPSA) | 57.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 115.02694 Da |
| Heavy Atoms | 8 |
| Complexity | 126.0 |
| Purity | ≥99.0% (acidimetric) |
| Melting Point | 93.0 |
| SMILES | C1CC(=O)N(C1=O)O |
| InChIKey | NQTADLQHYWFPDB-UHFFFAOYSA-N |
Product Description
Applications: N-Hydroxysuccinimide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Typical specifications: commercial lots are supplied at ≥99.0% (acidimetric). CoreyChem supplies N-Hydroxysuccinimide (CAS 6066-82-6) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, N-Hydroxysuccinimide (CAS 6066-82-6) has the molecular formula C4H5NO3 and a molecular weight of 115.03 g/mol. It is also known as N-Hydroxysuccinimide and 1-hydroxypyrrolidine-2,5-dione.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H315 - H318
Chemical Property Profile of N-Hydroxysuccinimide
Property Insights of N-Hydroxysuccinimide
The XLogP value of -1.4 indicates that N-Hydroxysuccinimide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 57.6 Ų, N-Hydroxysuccinimide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-Hydroxysuccinimide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-Hydroxysuccinimide?
The CAS number of N-Hydroxysuccinimide is 6066-82-6.
What is the molecular formula of N-Hydroxysuccinimide?
The molecular formula of N-Hydroxysuccinimide is C4H5NO3.
What is the molecular weight of N-Hydroxysuccinimide?
The molecular weight of N-Hydroxysuccinimide is 115.02694 g/mol.
What are the applications of N-Hydroxysuccinimide?
N-Hydroxysuccinimide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Typical specifications: commercial lots are supplied...
Where can I buy N-Hydroxysuccinimide?
You can request a quote for N-Hydroxysuccinimide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-Hydroxysuccinimide?
Yes, CoreyChem provides custom synthesis services for N-Hydroxysuccinimide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.