L-Leucine
TL;DR: L-Leucine (CAS 61-90-5) is a chemical compound with molecular formula C6H13NO2 and molecular weight 131.09464 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-amino-4-methylpentanoic acid
Also Known As: L-leucine, leucine, (S)-Leucine, H-Leu-OH, Leucin
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H13NO2 |
| Molecular Weight | 131.09464 g/mol |
| XLogP | -1.5 |
| Topological Polar Surface Area (TPSA) | 63.3 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 131.09464 Da |
| Heavy Atoms | 9 |
| Complexity | 101.0 |
| Melting Point | 293 |
| Boiling Point | Sublimes at 145-148 °C. Decomposes at 293-295 °C (rapid heating, sealed tube) |
| Density | 1.293 g/cu cm at 18 °C |
| Vapor Pressure | 0.00000001 [mmHg] |
| Solubility | 21500 |
| SMILES | CC(C)C[C@@H](C(=O)O)N |
| InChIKey | ROHFNLRQFUQHCH-YFKPBYRVSA-N |
Product Description
Applications: L-Leucine is used in biotechnology workflows and life-science research, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
L-Leucine (CAS 61-90-5) is a biotechnology compound with the molecular formula C6H13NO2 and a molecular weight of 131.09 g/mol. Key physical properties include a density of 1.293 g/cu cm at 18 °C g/cm³, a solubility: 21500. Synonyms include L-leucine and leucine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of L-Leucine
Property Insights of L-Leucine
The XLogP value of -1.5 indicates that L-Leucine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 63.3 Ų falls within the moderate polarity range, balancing permeability and solubility for L-Leucine. Following Lipinski's Rule of Five, L-Leucine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of L-Leucine?
The CAS number of L-Leucine is 61-90-5.
What is the molecular formula of L-Leucine?
The molecular formula of L-Leucine is C6H13NO2.
What is the molecular weight of L-Leucine?
The molecular weight of L-Leucine is 131.09464 g/mol.
What are the applications of L-Leucine?
L-Leucine is used in biotechnology workflows and life-science research, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy L-Leucine?
You can request a quote for L-Leucine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for L-Leucine?
Yes, CoreyChem provides custom synthesis services for L-Leucine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.