Rolipram
TL;DR: Rolipram (CAS 61413-54-5) is a chemical compound with molecular formula C16H21NO3 and molecular weight 275.15213 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one
Also Known As: rolipram, (R,S)-rolipram, Rolipramum, (+/-)-Rolipram, Adeo
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H21NO3 |
| Molecular Weight | 275.15213 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 47.6 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 275.15213 Da |
| Heavy Atoms | 20 |
| Complexity | 341.0 |
| SMILES | COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3 |
| InChIKey | HJORMJIFDVBMOB-UHFFFAOYSA-N |
Product Description
Applications: Rolipram is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Rolipram (CAS 61413-54-5) has the molecular formula C16H21NO3 and a molecular weight of 275.15 g/mol. Synonyms include rolipram and (R,S)-rolipram.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Rolipram
Property Insights of Rolipram
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rolipram. With a topological polar surface area (TPSA) of 47.6 Ų, Rolipram exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Rolipram has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Rolipram?
The CAS number of Rolipram is 61413-54-5.
What is the molecular formula of Rolipram?
The molecular formula of Rolipram is C16H21NO3.
What is the molecular weight of Rolipram?
The molecular weight of Rolipram is 275.15213 g/mol.
What are the applications of Rolipram?
Rolipram is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Rolipram?
You can request a quote for Rolipram directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Rolipram?
Yes, CoreyChem provides custom synthesis services for Rolipram and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.