Phenacetin
TL;DR: Phenacetin (CAS 62-44-2) is a chemical compound with molecular formula C10H13NO2 and molecular weight 179.09464 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(4-ethoxyphenyl)acetamide
Also Known As: phenacetin, Acetophenetidin, N-(4-Ethoxyphenyl)acetamide, Acetphenetidin, Acetophenetidine
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H13NO2 |
| Molecular Weight | 179.09464 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 38.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 3 |
| Exact Mass | 179.09464 Da |
| Heavy Atoms | 13 |
| Complexity | 162.0 |
| Melting Point | 273 to 280 °F (NTP, 1992) |
| Boiling Point | Decomposes (NTP, 1992) |
| Vapor Pressure | 6.29X10-7 mm Hg at 25 °C |
| Refractive Index | Index of refraction = 1.571at 25 °C/D |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | CCOC1=CC=C(C=C1)NC(=O)C |
| InChIKey | CPJSUEIXXCENMM-UHFFFAOYSA-N |
Product Description
Applications: Phenacetin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Phenacetin (CAS 62-44-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Phenacetin is a pharmaceutical intermediate identified by CAS number 62-44-2 and the molecular formula C10H13NO2 and a molecular weight of 179.09 g/mol. Physically, the compound has a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). It is also known as phenacetin and Acetophenetidin.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Phenacetin
Property Insights of Phenacetin
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Phenacetin. With a topological polar surface area (TPSA) of 38.3 Ų, Phenacetin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Phenacetin has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Phenacetin?
The CAS number of Phenacetin is 62-44-2.
What is the molecular formula of Phenacetin?
The molecular formula of Phenacetin is C10H13NO2.
What is the molecular weight of Phenacetin?
The molecular weight of Phenacetin is 179.09464 g/mol.
What are the applications of Phenacetin?
Phenacetin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Phenacetin (CAS 62-44-2) with custom...
Where can I buy Phenacetin?
You can request a quote for Phenacetin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Phenacetin?
Yes, CoreyChem provides custom synthesis services for Phenacetin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.