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pazopanib HCl structure
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pazopanib HCl

TL;DR: pazopanib HCl (CAS 635702-64-6) is a chemical compound with molecular formula C30H42O6 and molecular weight 498.29813 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.

[1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-13-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] deca-3,5-dienoate

Also Known As: pazopanib HCl, 4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl deca-3,5-dienoate, 5-(4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-ylamino)-2-methylbenzenesulfonamide hydrochloride

CAS Number
635702-64-6
Molecular Formula
C30H42O6
Molecular Weight
498.29813 g/mol
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Technical Specifications

Molecular FormulaC30H42O6
Molecular Weight498.29813 g/mol
XLogP3.8
Topological Polar Surface Area (TPSA)104.0 Ų
Hydrogen Bond Donors3
Hydrogen Bond Acceptors6
Rotatable Bonds9
Exact Mass498.29813 Da
Heavy Atoms36
Complexity1030.0
SMILESCCCCC=CC=CCC(=O)OC12CC(C3(C(C1C2(C)C)C=C(CC4(C3C=C(C4=O)C)O)CO)O)C
InChIKeyAZEXNJIEBDRVJS-UHFFFAOYSA-N

Product Description

Applications: pazopanib HCl is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies pazopanib HCl (CAS 635702-64-6) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.

pazopanib HCl (CAS 635702-64-6) is a fine chemical with the molecular formula C30H42O6 and a molecular weight of 498.3 g/mol. It is also known as pazopanib HCl and 4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulen-9a-yl deca-3,5-dienoate.

Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.

Chemical Property Profile of pazopanib HCl

XLogP
3.8
TPSA (Topological Polar Surface Area)
104.0
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
6
Rotatable Bonds
9
Heavy Atoms
36
Complexity
1030.0
Exact Mass
498.29813
Monoisotopic Mass
498.29813
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of pazopanib HCl

The XLogP value of 3.8 indicates that pazopanib HCl is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for pazopanib HCl. Following Lipinski's Rule of Five, pazopanib HCl has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the CAS number of pazopanib HCl?

The CAS number of pazopanib HCl is 635702-64-6.

What is the molecular formula of pazopanib HCl?

The molecular formula of pazopanib HCl is C30H42O6.

What is the molecular weight of pazopanib HCl?

The molecular weight of pazopanib HCl is 498.29813 g/mol.

What are the applications of pazopanib HCl?

pazopanib HCl is used in organic synthesis and process chemistry. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies pazopanib HCl (CAS 635702-64-6) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and...

Where can I buy pazopanib HCl?

You can request a quote for pazopanib HCl directly from CoreyChem. Contact us or email [email protected] for pricing and availability.

Does CoreyChem offer custom synthesis for pazopanib HCl?

Yes, CoreyChem provides custom synthesis services for pazopanib HCl and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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