Nisoldipine
TL;DR: Nisoldipine (CAS 63675-72-9) is a chemical compound with molecular formula C20H24N2O6 and molecular weight 388.16342 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-O-methyl 5-O-(2-methylpropyl) 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nisoldipine, Sular, Nisocor, Nisoldipin, Baymycard
Application Areas
Top 5 of 16 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H24N2O6 |
| Molecular Weight | 388.16342 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 110.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 388.16342 Da |
| Heavy Atoms | 28 |
| Complexity | 704.0 |
| Solubility | 5.77e-03 g/L |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCC(C)C)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC |
| InChIKey | VKQFCGNPDRICFG-UHFFFAOYSA-N |
Product Description
Applications: Nisoldipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Nisoldipine (CAS 63675-72-9) has the molecular formula C20H24N2O6 and a molecular weight of 388.16 g/mol. Reported properties include a solubility: 5.77e-03 g/L. Synonyms include nisoldipine and Sular.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nisoldipine
Property Insights of Nisoldipine
The XLogP value of 3.3 indicates that Nisoldipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nisoldipine. Following Lipinski's Rule of Five, Nisoldipine has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nisoldipine?
The CAS number of Nisoldipine is 63675-72-9.
What is the molecular formula of Nisoldipine?
The molecular formula of Nisoldipine is C20H24N2O6.
What is the molecular weight of Nisoldipine?
The molecular weight of Nisoldipine is 388.16342 g/mol.
What are the applications of Nisoldipine?
Nisoldipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nisoldipine?
You can request a quote for Nisoldipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nisoldipine?
Yes, CoreyChem provides custom synthesis services for Nisoldipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.