Bemegride
TL;DR: Bemegride (CAS 64-65-3) is a chemical compound with molecular formula C8H13NO2 and molecular weight 155.09464 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-ethyl-4-methylpiperidine-2,6-dione
Also Known As: bemegride, Methetharimide, Megimide, Megibal, 3-Ethyl-3-methylglutarimide
Application Areas
Top 5 of 10 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H13NO2 |
| Molecular Weight | 155.09464 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 46.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 155.09464 Da |
| Heavy Atoms | 11 |
| Complexity | 182.0 |
| Melting Point | 259 to 261 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | CCC1(CC(=O)NC(=O)C1)C |
| InChIKey | ORRZGUBHBVWWOP-UHFFFAOYSA-N |
Product Description
Applications: Bemegride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Bemegride is a pharmaceutical intermediate identified by CAS number 64-65-3 and the molecular formula C8H13NO2 and a molecular weight of 155.09 g/mol. Physically, the compound has a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). Synonyms include bemegride and Methetharimide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Bemegride
Property Insights of Bemegride
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Bemegride. With a topological polar surface area (TPSA) of 46.2 Ų, Bemegride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Bemegride has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Bemegride?
The CAS number of Bemegride is 64-65-3.
What is the molecular formula of Bemegride?
The molecular formula of Bemegride is C8H13NO2.
What is the molecular weight of Bemegride?
The molecular weight of Bemegride is 155.09464 g/mol.
What are the applications of Bemegride?
Bemegride is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Bemegride?
You can request a quote for Bemegride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bemegride?
Yes, CoreyChem provides custom synthesis services for Bemegride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.