Orotic Acid
TL;DR: Orotic Acid (CAS 65-86-1) is a chemical compound with molecular formula C5H4N2O4 and molecular weight 156.0171 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,4-dioxo-1H-pyrimidine-6-carboxylic acid
Also Known As: Orotic acid, 6-Carboxyuracil, Oropur, Orodin, Orotonin
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H4N2O4 |
| Molecular Weight | 156.0171 g/mol |
| XLogP | -1.4 |
| Topological Polar Surface Area (TPSA) | 95.5 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 156.0171 Da |
| Heavy Atoms | 11 |
| Complexity | 268.0 |
| Melting Point | 653 to 655 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 68 °F (NTP, 1992) |
| SMILES | C1=C(NC(=O)NC1=O)C(=O)O |
| InChIKey | PXQPEWDEAKTCGB-UHFFFAOYSA-N |
Product Description
Applications: Orotic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Orotic Acid (CAS 65-86-1) has the molecular formula C5H4N2O4 and a molecular weight of 156.02 g/mol. Reported properties include a solubility: less than 1 mg/mL at 68 °F (NTP, 1992). Synonyms include Orotic acid and 6-Carboxyuracil.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Orotic Acid
Property Insights of Orotic Acid
The XLogP value of -1.4 indicates that Orotic Acid is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 95.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Orotic Acid. Following Lipinski's Rule of Five, Orotic Acid has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Orotic Acid?
The CAS number of Orotic Acid is 65-86-1.
What is the molecular formula of Orotic Acid?
The molecular formula of Orotic Acid is C5H4N2O4.
What is the molecular weight of Orotic Acid?
The molecular weight of Orotic Acid is 156.0171 g/mol.
What are the applications of Orotic Acid?
Orotic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Orotic Acid?
You can request a quote for Orotic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Orotic Acid?
Yes, CoreyChem provides custom synthesis services for Orotic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.