Nimodipine
TL;DR: Nimodipine (CAS 66085-59-4) is a chemical compound with molecular formula C21H26N2O7 and molecular weight 418.174 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: nimodipine, Nimotop, Periplum, Admon, Nimodipino
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H26N2O7 |
| Molecular Weight | 418.174 g/mol |
| XLogP | 3.1 |
| Topological Polar Surface Area (TPSA) | 120.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 9 |
| Exact Mass | 418.174 Da |
| Heavy Atoms | 30 |
| Complexity | 736.0 |
| Melting Point | 125 |
| Solubility | 1.20e-02 g/L |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC |
| InChIKey | UIAGMCDKSXEBJQ-UHFFFAOYSA-N |
Product Description
Applications: Nimodipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nimodipine (CAS 66085-59-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Nimodipine is a pharmaceutical intermediate identified by CAS number 66085-59-4 and the molecular formula C21H26N2O7 and a molecular weight of 418.17 g/mol. Physically, the compound has a solubility: 1.20e-02 g/L. It is also known as nimodipine and Nimotop.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nimodipine
Property Insights of Nimodipine
The XLogP value of 3.1 indicates that Nimodipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 120.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Nimodipine. Following Lipinski's Rule of Five, Nimodipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nimodipine?
The CAS number of Nimodipine is 66085-59-4.
What is the molecular formula of Nimodipine?
The molecular formula of Nimodipine is C21H26N2O7.
What is the molecular weight of Nimodipine?
The molecular weight of Nimodipine is 418.174 g/mol.
What are the applications of Nimodipine?
Nimodipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nimodipine (CAS 66085-59-4) with custom...
Where can I buy Nimodipine?
You can request a quote for Nimodipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nimodipine?
Yes, CoreyChem provides custom synthesis services for Nimodipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.