17-Hydroxyprogesterone
TL;DR: 17-Hydroxyprogesterone (CAS 68-96-2) is a chemical compound with molecular formula C21H30O3 and molecular weight 330.21948 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
Also Known As: hydroxyprogesterone, 17-Hydroxyprogesterone, 17ALPHA-HYDROXYPROGESTERONE, 17a-Hydroxyprogesterone, Prodix
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H30O3 |
| Molecular Weight | 330.21948 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 54.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 330.21948 Da |
| Heavy Atoms | 24 |
| Complexity | 635.0 |
| Melting Point | 222-223 °C |
| Solubility | 0.00648 mg/mL |
| SMILES | CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O |
| InChIKey | DBPWSSGDRRHUNT-CEGNMAFCSA-N |
Product Description
Applications: 17-Hydroxyprogesterone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 17-Hydroxyprogesterone (CAS 68-96-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, 17-Hydroxyprogesterone (CAS 68-96-2) has the molecular formula C21H30O3 and a molecular weight of 330.22 g/mol. Reported properties include a solubility: 0.00648 mg/mL. It is also known as hydroxyprogesterone and 17-Hydroxyprogesterone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 17-Hydroxyprogesterone
Property Insights of 17-Hydroxyprogesterone
The XLogP value of 3.2 indicates that 17-Hydroxyprogesterone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.4 Ų, 17-Hydroxyprogesterone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 17-Hydroxyprogesterone has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 17-Hydroxyprogesterone?
The CAS number of 17-Hydroxyprogesterone is 68-96-2.
What is the molecular formula of 17-Hydroxyprogesterone?
The molecular formula of 17-Hydroxyprogesterone is C21H30O3.
What is the molecular weight of 17-Hydroxyprogesterone?
The molecular weight of 17-Hydroxyprogesterone is 330.21948 g/mol.
What are the applications of 17-Hydroxyprogesterone?
17-Hydroxyprogesterone is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 17-Hydroxyprogesterone (CAS...
Where can I buy 17-Hydroxyprogesterone?
You can request a quote for 17-Hydroxyprogesterone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 17-Hydroxyprogesterone?
Yes, CoreyChem provides custom synthesis services for 17-Hydroxyprogesterone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.