Nitidine
TL;DR: Nitidine (CAS 6872-57-7) is a chemical compound with molecular formula C21H18NO4+ and molecular weight 348.1236 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,3-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
Also Known As: Nitidine, Nitidine chloride, nitidine cation, oxynitdine, Nididine
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H18NO4+ |
| Molecular Weight | 348.1236 g/mol |
| XLogP | 4.6 |
| Topological Polar Surface Area (TPSA) | 40.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 348.1236 Da |
| Heavy Atoms | 26 |
| Complexity | 516.0 |
| SMILES | C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)OC |
| InChIKey | KKMPSGJPCCJYRV-UHFFFAOYSA-N |
Product Description
Applications: Nitidine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Nitidine is a pharmaceutical intermediate identified by CAS number 6872-57-7 and the molecular formula C21H18NO4+ and a molecular weight of 348.12 g/mol. Synonyms include Nitidine and Nitidine chloride.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nitidine
Property Insights of Nitidine
The XLogP value of 4.6 indicates that Nitidine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.8 Ų, Nitidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nitidine has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nitidine?
The CAS number of Nitidine is 6872-57-7.
What is the molecular formula of Nitidine?
The molecular formula of Nitidine is C21H18NO4+.
What is the molecular weight of Nitidine?
The molecular weight of Nitidine is 348.1236 g/mol.
What are the applications of Nitidine?
Nitidine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Nitidine?
You can request a quote for Nitidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nitidine?
Yes, CoreyChem provides custom synthesis services for Nitidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.