4-Hydroxyproline
TL;DR: 4-Hydroxyproline (CAS 6912-67-0) is a chemical compound with molecular formula C5H9NO3 and molecular weight 131.05824 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-hydroxypyrrolidine-2-carboxylic acid
Also Known As: 4-hydroxyproline, L-Hydroxyproline, 4-hydroxypyrrolidine-2-carboxylic acid, hydroxyproline, cis-4-Hydroxy-D-proline
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C5H9NO3 |
| Molecular Weight | 131.05824 g/mol |
| XLogP | -3.3 |
| Topological Polar Surface Area (TPSA) | 69.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 131.05824 Da |
| Heavy Atoms | 9 |
| Complexity | 125.0 |
| SMILES | C1C(CNC1C(=O)O)O |
| InChIKey | PMMYEEVYMWASQN-UHFFFAOYSA-N |
Product Description
Applications: 4-Hydroxyproline is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
4-Hydroxyproline (CAS 6912-67-0) is a pharmaceutical intermediate with the molecular formula C5H9NO3 and a molecular weight of 131.06 g/mol. Synonyms include 4-hydroxyproline and L-Hydroxyproline.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 4-Hydroxyproline
Property Insights of 4-Hydroxyproline
The XLogP value of -3.3 indicates that 4-Hydroxyproline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 69.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Hydroxyproline. Following Lipinski's Rule of Five, 4-Hydroxyproline has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Hydroxyproline?
The CAS number of 4-Hydroxyproline is 6912-67-0.
What is the molecular formula of 4-Hydroxyproline?
The molecular formula of 4-Hydroxyproline is C5H9NO3.
What is the molecular weight of 4-Hydroxyproline?
The molecular weight of 4-Hydroxyproline is 131.05824 g/mol.
What are the applications of 4-Hydroxyproline?
4-Hydroxyproline is used in pharmaceutical synthesis routes and API production, as well as biotechnology workflows and life-science research. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to...
Where can I buy 4-Hydroxyproline?
You can request a quote for 4-Hydroxyproline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Hydroxyproline?
Yes, CoreyChem provides custom synthesis services for 4-Hydroxyproline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.