Melatonin
TL;DR: Melatonin (CAS 73-31-4) is a chemical compound with molecular formula C13H16N2O2 and molecular weight 232.12119 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
Also Known As: Melatonin, Melatonine, N-Acetyl-5-methoxytryptamine, Circadin, Melatol
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H16N2O2 |
| Molecular Weight | 232.12119 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 54.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 4 |
| Exact Mass | 232.12119 Da |
| Heavy Atoms | 17 |
| Complexity | 270.0 |
| Melting Point | 117 |
| Solubility | In water, 2 g/L at 20 °C; 5 g/L at 50 °C |
| SMILES | CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC |
| InChIKey | DRLFMBDRBRZALE-UHFFFAOYSA-N |
Product Description
Applications: Melatonin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, Melatonin (CAS 73-31-4) has the molecular formula C13H16N2O2 and a molecular weight of 232.12 g/mol. Reported properties include a solubility: In water, 2 g/L at 20 °C; 5 g/L at 50 °C. Synonyms include Melatonin and Melatonine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Melatonin
Property Insights of Melatonin
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Melatonin. With a topological polar surface area (TPSA) of 54.1 Ų, Melatonin exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Melatonin has 2 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Melatonin?
The CAS number of Melatonin is 73-31-4.
What is the molecular formula of Melatonin?
The molecular formula of Melatonin is C13H16N2O2.
What is the molecular weight of Melatonin?
The molecular weight of Melatonin is 232.12119 g/mol.
What are the applications of Melatonin?
Melatonin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Melatonin?
You can request a quote for Melatonin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Melatonin?
Yes, CoreyChem provides custom synthesis services for Melatonin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.