Doxazosin
TL;DR: Doxazosin (CAS 74191-85-8) is a chemical compound with molecular formula C23H25N5O5 and molecular weight 451.18558 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
Also Known As: doxazosin, Doxazosine, Doxazosinum, Doxazosina, Doxazosin mesylate
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C23H25N5O5 |
| Molecular Weight | 451.18558 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 112.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 451.18558 Da |
| Heavy Atoms | 33 |
| Complexity | 678.0 |
| Melting Point | 275-277 |
| Boiling Point | 718 |
| Solubility | 0.8% |
| SMILES | COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4COC5=CC=CC=C5O4)N)OC |
| InChIKey | RUZYUOTYCVRMRZ-UHFFFAOYSA-N |
Product Description
Applications: Doxazosin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Doxazosin (CAS 74191-85-8) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Doxazosin (CAS 74191-85-8) is a pharmaceutical intermediate with the molecular formula C23H25N5O5 and a molecular weight of 451.19 g/mol. Key physical properties include a solubility: 0.8%. It is also known as doxazosin and Doxazosine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Doxazosin
Property Insights of Doxazosin
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Doxazosin. The TPSA of 112.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Doxazosin. Following Lipinski's Rule of Five, Doxazosin has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Doxazosin?
The CAS number of Doxazosin is 74191-85-8.
What is the molecular formula of Doxazosin?
The molecular formula of Doxazosin is C23H25N5O5.
What is the molecular weight of Doxazosin?
The molecular weight of Doxazosin is 451.18558 g/mol.
What are the applications of Doxazosin?
Doxazosin is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Doxazosin (CAS 74191-85-8) with custom...
Where can I buy Doxazosin?
You can request a quote for Doxazosin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Doxazosin?
Yes, CoreyChem provides custom synthesis services for Doxazosin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.