Isradipine
TL;DR: Isradipine (CAS 75695-93-1) is a chemical compound with molecular formula C19H21N3O5 and molecular weight 371.14813 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-O-methyl 5-O-propan-2-yl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: isradipine, DynaCirc, Isradipin, Isrodipine, Lomir
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H21N3O5 |
| Molecular Weight | 371.14813 g/mol |
| XLogP | 4.3 |
| Topological Polar Surface Area (TPSA) | 104.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 371.14813 Da |
| Heavy Atoms | 27 |
| Complexity | 685.0 |
| Melting Point | 168-170 °C |
| Solubility | Practically insoluble (< 10 mg/L at 37 °C) |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC |
| InChIKey | HMJIYCCIJYRONP-UHFFFAOYSA-N |
Product Description
Applications: Isradipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Isradipine (CAS 75695-93-1) is a pharmaceutical intermediate with the molecular formula C19H21N3O5 and a molecular weight of 371.15 g/mol. Key physical properties include a solubility: Practically insoluble (< 10 mg/L at 37 °C). Synonyms include isradipine and DynaCirc.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Isradipine
Property Insights of Isradipine
The XLogP value of 4.3 indicates that Isradipine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Isradipine. Following Lipinski's Rule of Five, Isradipine has 1 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Isradipine?
The CAS number of Isradipine is 75695-93-1.
What is the molecular formula of Isradipine?
The molecular formula of Isradipine is C19H21N3O5.
What is the molecular weight of Isradipine?
The molecular weight of Isradipine is 371.14813 g/mol.
What are the applications of Isradipine?
Isradipine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Isradipine?
You can request a quote for Isradipine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Isradipine?
Yes, CoreyChem provides custom synthesis services for Isradipine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.