L-trans-Epoxysuccinyl-Leu-3-methylbutylamide
TL;DR: L-trans-Epoxysuccinyl-Leu-3-methylbutylamide (CAS 76684-89-4) is a chemical compound with molecular formula C15H26N2O5 and molecular weight 314.18417 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-[[4-methyl-1-(3-methylbutylamino)-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Also Known As: Loxistatin acid, Vismodegib, e-64c, E 64c, Loxistatin Acid (E-64C)
Application Areas
Top 5 of 1 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H26N2O5 |
| Molecular Weight | 314.18417 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 108.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 9 |
| Exact Mass | 314.18417 Da |
| Heavy Atoms | 22 |
| Complexity | 422.0 |
| SMILES | CC(C)CCNC(=O)C(CC(C)C)NC(=O)C1C(O1)C(=O)O |
| InChIKey | SCMSYZJDIQPSDI-UHFFFAOYSA-N |
Product Description
Applications: L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is used in heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, L-trans-Epoxysuccinyl-Leu-3-methylbutylamide (CAS 76684-89-4) has the molecular formula C15H26N2O5 and a molecular weight of 314.18 g/mol. Synonyms include Loxistatin acid and Vismodegib.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide
Property Insights of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide. The TPSA of 108.0 Ų falls within the moderate polarity range, balancing permeability and solubility for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide. Following Lipinski's Rule of Five, L-trans-Epoxysuccinyl-Leu-3-methylbutylamide has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?
The CAS number of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is 76684-89-4.
What is the molecular formula of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?
The molecular formula of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is C15H26N2O5.
What is the molecular weight of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?
The molecular weight of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is 314.18417 g/mol.
What are the applications of L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?
L-trans-Epoxysuccinyl-Leu-3-methylbutylamide is used in heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton...
Where can I buy L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?
You can request a quote for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide?
Yes, CoreyChem provides custom synthesis services for L-trans-Epoxysuccinyl-Leu-3-methylbutylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.