Glutethimide
TL;DR: Glutethimide (CAS 77-21-4) is a chemical compound with molecular formula C13H15NO2 and molecular weight 217.11028 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-ethyl-3-phenylpiperidine-2,6-dione
Also Known As: glutethimide, Doriden, Sarodormin, Elrodorm, Noxyron
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H15NO2 |
| Molecular Weight | 217.11028 g/mol |
| XLogP | 1.9 |
| Topological Polar Surface Area (TPSA) | 46.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 217.11028 Da |
| Heavy Atoms | 16 |
| Complexity | 294.0 |
| Melting Point | 78-81 |
| Solubility | 999 |
| SMILES | CCC1(CCC(=O)NC1=O)C2=CC=CC=C2 |
| InChIKey | JMBQKKAJIKAWKF-UHFFFAOYSA-N |
Product Description
Applications: Glutethimide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Glutethimide (CAS 77-21-4) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Glutethimide is a pharmaceutical intermediate identified by CAS number 77-21-4 and the molecular formula C13H15NO2 and a molecular weight of 217.11 g/mol. Physically, the compound has a solubility: 999. It is also known as glutethimide and Doriden.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Glutethimide
Property Insights of Glutethimide
The XLogP value of 1.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Glutethimide. With a topological polar surface area (TPSA) of 46.2 Ų, Glutethimide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Glutethimide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Glutethimide?
The CAS number of Glutethimide is 77-21-4.
What is the molecular formula of Glutethimide?
The molecular formula of Glutethimide is C13H15NO2.
What is the molecular weight of Glutethimide?
The molecular weight of Glutethimide is 217.11028 g/mol.
What are the applications of Glutethimide?
Glutethimide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Glutethimide (CAS 77-21-4) with custom...
Where can I buy Glutethimide?
You can request a quote for Glutethimide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Glutethimide?
Yes, CoreyChem provides custom synthesis services for Glutethimide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.