Nafamostat
TL;DR: Nafamostat (CAS 81525-10-2) is a chemical compound with molecular formula C19H17N5O2 and molecular weight 347.1382 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate
Also Known As: Nafamostat, Nafamostat mesylate, Nafamostatum, Nafamstat, nafamostat mesilate
Application Areas
Top 5 of 11 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C19H17N5O2 |
| Molecular Weight | 347.1382 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 141.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 347.1382 Da |
| Heavy Atoms | 26 |
| Complexity | 552.0 |
| SMILES | C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N |
| InChIKey | MQQNFDZXWVTQEH-UHFFFAOYSA-N |
Product Description
Applications: Nafamostat is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nafamostat (CAS 81525-10-2) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Nafamostat is a pharmaceutical intermediate identified by CAS number 81525-10-2 and the molecular formula C19H17N5O2 and a molecular weight of 347.14 g/mol. It is also known as Nafamostat and Nafamostat mesylate.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Nafamostat
Property Insights of Nafamostat
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nafamostat. The TPSA of 141.0 Ų indicates high polarity, suggesting Nafamostat may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Nafamostat has 4 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nafamostat?
The CAS number of Nafamostat is 81525-10-2.
What is the molecular formula of Nafamostat?
The molecular formula of Nafamostat is C19H17N5O2.
What is the molecular weight of Nafamostat?
The molecular weight of Nafamostat is 347.1382 g/mol.
What are the applications of Nafamostat?
Nafamostat is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Nafamostat (CAS 81525-10-2) with custom...
Where can I buy Nafamostat?
You can request a quote for Nafamostat directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nafamostat?
Yes, CoreyChem provides custom synthesis services for Nafamostat and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.