Phthalimide
TL;DR: Phthalimide (CAS 85-41-6) is a chemical compound with molecular formula C8H5NO2 and molecular weight 147.03203 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
isoindole-1,3-dione
Also Known As: PHTHALIMIDE, O-Phthalimide, Isoindole-1,3-dione, o-Phthalic imide, isoindoline-1,3-dione
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H5NO2 |
| Molecular Weight | 147.03203 g/mol |
| XLogP | 1.1 |
| Topological Polar Surface Area (TPSA) | 46.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 147.03203 Da |
| Heavy Atoms | 11 |
| Complexity | 190.0 |
| Melting Point | 460 °F (NTP, 1992) |
| Boiling Point | Sublimes (NTP, 1992) |
| Vapor Pressure | 0.00000001 [mmHg] |
| Solubility | less than 1 mg/mL at 67.1 °F (NTP, 1992) |
| SMILES | C1=CC=C2C(=C1)C(=O)NC2=O |
| InChIKey | XKJCHHZQLQNZHY-UHFFFAOYSA-N |
Product Description
Applications: Phthalimide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A heterocyclic building block supplied by CoreyChem, Phthalimide (CAS 85-41-6) has the molecular formula C8H5NO2 and a molecular weight of 147.03 g/mol. Reported properties include a solubility: less than 1 mg/mL at 67.1 °F (NTP, 1992). Synonyms include PHTHALIMIDE and O-Phthalimide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Phthalimide
Property Insights of Phthalimide
The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Phthalimide. With a topological polar surface area (TPSA) of 46.2 Ų, Phthalimide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Phthalimide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Phthalimide?
The CAS number of Phthalimide is 85-41-6.
What is the molecular formula of Phthalimide?
The molecular formula of Phthalimide is C8H5NO2.
What is the molecular weight of Phthalimide?
The molecular weight of Phthalimide is 147.03203 g/mol.
What are the applications of Phthalimide?
Phthalimide is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Phthalimide?
You can request a quote for Phthalimide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Phthalimide?
Yes, CoreyChem provides custom synthesis services for Phthalimide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.