Tetrahydrophthalic anhydride
TL;DR: Tetrahydrophthalic anhydride (CAS 85-43-8) is a chemical compound with molecular formula C8H8O3 and molecular weight 152.04735 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3a,4,7,7a-tetrahydro-2-benzofuran-1,3-dione
Also Known As: TETRAHYDROPHTHALIC ANHYDRIDE, THPA, Rikacid TH, 1,2,3,6-Tetrahydrophthalic anhydride, Tetrahydroftalanhydrid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.04735 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 43.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 152.04735 Da |
| Heavy Atoms | 11 |
| Complexity | 218.0 |
| Melting Point | Crystals from petroleum ether. MP: 103.5 °C. Soluble in ethanol, acetone, chloroform, benzene; slightly soluble in petroleum ether. /cis-1,2,3,6-Tetrahydrophthalic anhydride/ |
| Boiling Point | at 6.7kPa: 195 °C |
| Density | 1.20 at 105 °C |
| Flash Point | 315 °F (157 °C) Open cup |
| Vapor Pressure | 0.05 [mmHg] |
| Solubility | Slightly soluble in petroleum ether and ethyl ether; soluble in benzene |
| SMILES | C1C=CCC2C1C(=O)OC2=O |
| InChIKey | KMOUUZVZFBCRAM-UHFFFAOYSA-N |
Product Description
Applications: Tetrahydrophthalic anhydride is used in polymer chemistry and functional materials synthesis, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Tetrahydrophthalic anhydride is a polymer intermediate identified by CAS number 85-43-8 and the molecular formula C8H8O3 and a molecular weight of 152.05 g/mol. Physically, the compound has a density of 1.20 at 105 °C g/cm³, a solubility: Slightly soluble in petroleum ether and ethyl ether; soluble in benzene. Synonyms include TETRAHYDROPHTHALIC ANHYDRIDE and THPA.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Tetrahydrophthalic anhydride
Property Insights of Tetrahydrophthalic anhydride
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tetrahydrophthalic anhydride. With a topological polar surface area (TPSA) of 43.4 Ų, Tetrahydrophthalic anhydride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tetrahydrophthalic anhydride has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Tetrahydrophthalic anhydride?
The CAS number of Tetrahydrophthalic anhydride is 85-43-8.
What is the molecular formula of Tetrahydrophthalic anhydride?
The molecular formula of Tetrahydrophthalic anhydride is C8H8O3.
What is the molecular weight of Tetrahydrophthalic anhydride?
The molecular weight of Tetrahydrophthalic anhydride is 152.04735 g/mol.
What are the applications of Tetrahydrophthalic anhydride?
Tetrahydrophthalic anhydride is used in polymer chemistry and functional materials synthesis, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog...
Where can I buy Tetrahydrophthalic anhydride?
You can request a quote for Tetrahydrophthalic anhydride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tetrahydrophthalic anhydride?
Yes, CoreyChem provides custom synthesis services for Tetrahydrophthalic anhydride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.