Dibucaine
TL;DR: Dibucaine (CAS 85-79-0) is a chemical compound with molecular formula C20H29N3O2 and molecular weight 343.22598 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide
Also Known As: dibucaine, Cinchocaine, Nupercainal, Nupercaine, Dermacaine
Application Areas
Top 5 of 18 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C20H29N3O2 |
| Molecular Weight | 343.22598 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 54.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 10 |
| Exact Mass | 343.22598 Da |
| Heavy Atoms | 25 |
| Complexity | 387.0 |
| Melting Point | 99-101 °C (HCl salt) |
| Solubility | 42 |
| SMILES | CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC |
| InChIKey | PUFQVTATUTYEAL-UHFFFAOYSA-N |
Product Description
Applications: Dibucaine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
Dibucaine is a pharmaceutical intermediate identified by CAS number 85-79-0 and the molecular formula C20H29N3O2 and a molecular weight of 343.23 g/mol. Physically, the compound has a solubility: 42. Synonyms include dibucaine and Cinchocaine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Dibucaine
Property Insights of Dibucaine
The XLogP value of 4.4 indicates that Dibucaine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.5 Ų, Dibucaine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Dibucaine has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Dibucaine?
The CAS number of Dibucaine is 85-79-0.
What is the molecular formula of Dibucaine?
The molecular formula of Dibucaine is C20H29N3O2.
What is the molecular weight of Dibucaine?
The molecular weight of Dibucaine is 343.22598 g/mol.
What are the applications of Dibucaine?
Dibucaine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy Dibucaine?
You can request a quote for Dibucaine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Dibucaine?
Yes, CoreyChem provides custom synthesis services for Dibucaine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.