1-Hydroxy-2-naphthoic acid
TL;DR: 1-Hydroxy-2-naphthoic acid (CAS 86-48-6) is a chemical compound with molecular formula C11H8O3 and molecular weight 188.04735 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-hydroxynaphthalene-2-carboxylic acid
Also Known As: 1-Hydroxy-2-naphthoic acid, Xinafoic acid, 1-hydroxynaphthalene-2-carboxylic acid, 2-Carboxy-1-naphthol, 1-Naphthol-2-carboxylic acid
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C11H8O3 |
| Molecular Weight | 188.04735 g/mol |
| XLogP | 2.6 |
| Topological Polar Surface Area (TPSA) | 57.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 188.04735 Da |
| Heavy Atoms | 14 |
| Complexity | 227.0 |
| SMILES | C1=CC=C2C(=C1)C=CC(=C2O)C(=O)O |
| InChIKey | SJJCQDRGABAVBB-UHFFFAOYSA-N |
Product Description
Applications: 1-Hydroxy-2-naphthoic acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1-Hydroxy-2-naphthoic acid (CAS 86-48-6) is a pharmaceutical intermediate with the molecular formula C11H8O3 and a molecular weight of 188.05 g/mol. Synonyms include 1-Hydroxy-2-naphthoic acid and Xinafoic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Hydroxy-2-naphthoic acid
Property Insights of 1-Hydroxy-2-naphthoic acid
The XLogP value of 2.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Hydroxy-2-naphthoic acid. With a topological polar surface area (TPSA) of 57.5 Ų, 1-Hydroxy-2-naphthoic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Hydroxy-2-naphthoic acid has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Hydroxy-2-naphthoic acid?
The CAS number of 1-Hydroxy-2-naphthoic acid is 86-48-6.
What is the molecular formula of 1-Hydroxy-2-naphthoic acid?
The molecular formula of 1-Hydroxy-2-naphthoic acid is C11H8O3.
What is the molecular weight of 1-Hydroxy-2-naphthoic acid?
The molecular weight of 1-Hydroxy-2-naphthoic acid is 188.04735 g/mol.
What are the applications of 1-Hydroxy-2-naphthoic acid?
1-Hydroxy-2-naphthoic acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item...
Where can I buy 1-Hydroxy-2-naphthoic acid?
You can request a quote for 1-Hydroxy-2-naphthoic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Hydroxy-2-naphthoic acid?
Yes, CoreyChem provides custom synthesis services for 1-Hydroxy-2-naphthoic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.