1-Naphthaleneacetamide
TL;DR: 1-Naphthaleneacetamide (CAS 86-86-2) is a chemical compound with molecular formula C12H11NO and molecular weight 185.08406 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-naphthalen-1-ylacetamide
Also Known As: 1-NAPHTHALENEACETAMIDE, 1-Naphthylacetamide, Rootone, Naphthaleneacetamide, Frufix
Application Areas
Top 5 of 17 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C12H11NO |
| Molecular Weight | 185.08406 g/mol |
| XLogP | 2.1 |
| Topological Polar Surface Area (TPSA) | 43.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 2 |
| Exact Mass | 185.08406 Da |
| Heavy Atoms | 14 |
| Complexity | 214.0 |
| Melting Point | 184 °C |
| Solubility | 0.039 mg/mL at 40 °C |
| SMILES | C1=CC=C2C(=C1)C=CC=C2CC(=O)N |
| InChIKey | XFNJVKMNNVCYEK-UHFFFAOYSA-N |
Product Description
Applications: 1-Naphthaleneacetamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
A pharmaceutical intermediate supplied by CoreyChem, 1-Naphthaleneacetamide (CAS 86-86-2) has the molecular formula C12H11NO and a molecular weight of 185.08 g/mol. Reported properties include a solubility: 0.039 mg/mL at 40 °C. Synonyms include 1-NAPHTHALENEACETAMIDE and 1-Naphthylacetamide.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Naphthaleneacetamide
Property Insights of 1-Naphthaleneacetamide
The XLogP value of 2.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Naphthaleneacetamide. With a topological polar surface area (TPSA) of 43.1 Ų, 1-Naphthaleneacetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Naphthaleneacetamide has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Naphthaleneacetamide?
The CAS number of 1-Naphthaleneacetamide is 86-86-2.
What is the molecular formula of 1-Naphthaleneacetamide?
The molecular formula of 1-Naphthaleneacetamide is C12H11NO.
What is the molecular weight of 1-Naphthaleneacetamide?
The molecular weight of 1-Naphthaleneacetamide is 185.08406 g/mol.
What are the applications of 1-Naphthaleneacetamide?
1-Naphthaleneacetamide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 1-Naphthaleneacetamide?
You can request a quote for 1-Naphthaleneacetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Naphthaleneacetamide?
Yes, CoreyChem provides custom synthesis services for 1-Naphthaleneacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.