N-vinyl-2-pyrrolidone
TL;DR: N-vinyl-2-pyrrolidone (CAS 88-12-0) is a chemical compound with molecular formula C6H9NO and molecular weight 111.06841 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-ethenylpyrrolidin-2-one
Also Known As: N-VINYL-2-PYRROLIDONE, N-Vinylpyrrolidone, 1-Vinyl-2-pyrrolidone, Vinylpyrrolidone, 1-vinylpyrrolidin-2-one
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C6H9NO |
| Molecular Weight | 111.06841 g/mol |
| XLogP | 0.4 |
| Topological Polar Surface Area (TPSA) | 20.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 111.06841 Da |
| Heavy Atoms | 8 |
| Complexity | 120.0 |
| Melting Point | 13 °C |
| Boiling Point | 96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg |
| Density | 1.04 @ 24 °C/4 °C |
| Flash Point | 95 °C |
| Vapor Pressure | 0.1 [mmHg] |
| Refractive Index | Index of refraction = 1.511 @ 25 °C/D |
| Solubility | Soluble in water and many organic solvents |
| SMILES | C=CN1CCCC1=O |
| InChIKey | WHNWPMSKXPGLAX-UHFFFAOYSA-N |
Product Description
Applications: N-vinyl-2-pyrrolidone is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
N-vinyl-2-pyrrolidone (CAS 88-12-0) is a pharmaceutical intermediate with the molecular formula C6H9NO and a molecular weight of 111.07 g/mol. Key physical properties include a density of 1.04 @ 24 °C/4 °C g/cm³, a solubility: Soluble in water and many organic solvents. Synonyms include N-VINYL-2-PYRROLIDONE and N-Vinylpyrrolidone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of N-vinyl-2-pyrrolidone
Property Insights of N-vinyl-2-pyrrolidone
The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-vinyl-2-pyrrolidone. With a topological polar surface area (TPSA) of 20.3 Ų, N-vinyl-2-pyrrolidone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-vinyl-2-pyrrolidone has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of N-vinyl-2-pyrrolidone?
The CAS number of N-vinyl-2-pyrrolidone is 88-12-0.
What is the molecular formula of N-vinyl-2-pyrrolidone?
The molecular formula of N-vinyl-2-pyrrolidone is C6H9NO.
What is the molecular weight of N-vinyl-2-pyrrolidone?
The molecular weight of N-vinyl-2-pyrrolidone is 111.06841 g/mol.
What are the applications of N-vinyl-2-pyrrolidone?
N-vinyl-2-pyrrolidone is used in pharmaceutical synthesis routes and API production, as well as polymer chemistry and functional materials synthesis. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project...
Where can I buy N-vinyl-2-pyrrolidone?
You can request a quote for N-vinyl-2-pyrrolidone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for N-vinyl-2-pyrrolidone?
Yes, CoreyChem provides custom synthesis services for N-vinyl-2-pyrrolidone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.