5-Aminosalicylic Acid
TL;DR: 5-Aminosalicylic Acid (CAS 89-57-6) is a chemical compound with molecular formula C7H7NO3 and molecular weight 153.04259 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-amino-2-hydroxybenzoic acid
Also Known As: mesalamine, 5-Aminosalicylic acid, Mesalazine, 5-Amino-2-hydroxybenzoic acid, Pentasa
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C7H7NO3 |
| Molecular Weight | 153.04259 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 83.6 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 1 |
| Exact Mass | 153.04259 Da |
| Heavy Atoms | 11 |
| Complexity | 160.0 |
| Melting Point | 536 °F (decomposes) (NTP, 1992) |
| Vapor Pressure | 0.00000006 [mmHg] |
| Solubility | less than 1 mg/mL at 70 °F (NTP, 1992) |
| SMILES | C1=CC(=C(C=C1N)C(=O)O)O |
| InChIKey | KBOPZPXVLCULAV-UHFFFAOYSA-N |
Product Description
Applications: 5-Aminosalicylic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
5-Aminosalicylic Acid (CAS 89-57-6) is a pharmaceutical intermediate with the molecular formula C7H7NO3 and a molecular weight of 153.04 g/mol. Key physical properties include a solubility: less than 1 mg/mL at 70 °F (NTP, 1992). Synonyms include mesalamine and 5-Aminosalicylic acid.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5-Aminosalicylic Acid
Property Insights of 5-Aminosalicylic Acid
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Aminosalicylic Acid. The TPSA of 83.6 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Aminosalicylic Acid. Following Lipinski's Rule of Five, 5-Aminosalicylic Acid has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Aminosalicylic Acid?
The CAS number of 5-Aminosalicylic Acid is 89-57-6.
What is the molecular formula of 5-Aminosalicylic Acid?
The molecular formula of 5-Aminosalicylic Acid is C7H7NO3.
What is the molecular weight of 5-Aminosalicylic Acid?
The molecular weight of 5-Aminosalicylic Acid is 153.04259 g/mol.
What are the applications of 5-Aminosalicylic Acid?
5-Aminosalicylic Acid is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy 5-Aminosalicylic Acid?
You can request a quote for 5-Aminosalicylic Acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Aminosalicylic Acid?
Yes, CoreyChem provides custom synthesis services for 5-Aminosalicylic Acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.