Guaiacol
TL;DR: Guaiacol (CAS 90-05-1) is a chemical compound with molecular formula C7H8O2 and molecular weight 124.05243 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-methoxyphenol
Also Known As: guaiacol, 2-Methoxyphenol, o-Methoxyphenol, 2-Hydroxyanisole, Guaiastil
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C7H8O2 |
| Molecular Weight | 124.05243 g/mol |
| XLogP | 1.3 |
| Topological Polar Surface Area (TPSA) | 29.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 124.05243 Da |
| Heavy Atoms | 9 |
| Complexity | 83.0 |
| Purity | ≥99% |
| Melting Point | SOLIDIFIES at 82.4 °F (NTP, 1992) |
| Boiling Point | 399 to 403 °F at 760 mmHg (NTP, 1992) |
| Density | 1.13 at 70.5 °F (NTP, 1992) - Denser than water; will sink |
| Flash Point | 180 °F (NTP, 1992) |
| Vapor Pressure | 5 mmHg at 174 °F (NTP, 1992) |
| Refractive Index | Index of refraction: 1.5429 at 20 °C/D |
| Solubility | Slightly soluble (NTP, 1992) |
| SMILES | COC1=CC=CC=C1O |
| InChIKey | LHGVFZTZFXWLCP-UHFFFAOYSA-N |
Product Description
Applications: Guaiacol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Typical specifications: commercial lots are supplied at ≥99%. CoreyChem supplies Guaiacol (CAS 90-05-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
Guaiacol (CAS 90-05-1) is a pharmaceutical intermediate with the molecular formula C7H8O2 and a molecular weight of 124.05 g/mol. Key physical properties include a density of 1.13 at 70.5 °F (NTP, 1992) - Denser than water; will sink g/cm³, a solubility: Slightly soluble (NTP, 1992). It is also known as guaiacol and 2-Methoxyphenol.
CoreyChem provides it with COA documentation, and custom synthesis from milligram to multi-kilogram scales is available on request. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H302, H315, H319
Chemical Property Profile of Guaiacol
Property Insights of Guaiacol
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Guaiacol. With a topological polar surface area (TPSA) of 29.5 Ų, Guaiacol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Guaiacol has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Guaiacol?
The CAS number of Guaiacol is 90-05-1.
What is the molecular formula of Guaiacol?
The molecular formula of Guaiacol is C7H8O2.
What is the molecular weight of Guaiacol?
The molecular weight of Guaiacol is 124.05243 g/mol.
What are the applications of Guaiacol?
Guaiacol is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Typical specifications: commercial lots are supplied at ≥99%....
Where can I buy Guaiacol?
You can request a quote for Guaiacol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Guaiacol?
Yes, CoreyChem provides custom synthesis services for Guaiacol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.