1-Naphthol
TL;DR: 1-Naphthol (CAS 90-15-3) is a chemical compound with molecular formula C10H8O and molecular weight 144.05751 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
naphthalen-1-ol
Also Known As: 1-NAPHTHOL, naphthalen-1-ol, alpha-naphthol, 1-Naphthalenol, 1-Hydroxynaphthalene
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H8O |
| Molecular Weight | 144.05751 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 20.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 144.05751 Da |
| Heavy Atoms | 11 |
| Complexity | 133.0 |
| Purity | ≥99% |
| Melting Point | 96 °C |
| Boiling Point | 288 °C |
| Density | 1.0954 at 98.7 °C/4 °C |
| Flash Point | 153 °C (open cup) |
| Vapor Pressure | 0.000274 [mmHg] |
| Refractive Index | Index of refraction: 1.6224 at 99 °C/D |
| Solubility | In water, 866 mg/L at 25 °C |
| SMILES | C1=CC=C2C(=C1)C=CC=C2O |
| InChIKey | KJCVRFUGPWSIIH-UHFFFAOYSA-N |
Product Description
Applications: 1-Naphthol is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at ≥99%. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
1-Naphthol is a heterocyclic building block identified by CAS number 90-15-3 and the molecular formula C10H8O and a molecular weight of 144.06 g/mol. Physically, the compound has a density of 1.0954 at 98.7 °C/4 °C g/cm³, a solubility: In water, 866 mg/L at 25 °C. Synonyms include 1-NAPHTHOL and naphthalen-1-ol.
Custom synthesis (mg to ton scale), HPLC/NMR/MS analytical support, and complete COA/MSDS documentation are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Safety Information
H302, H311, H315, H317, H318, H335, H371, H410
Chemical Property Profile of 1-Naphthol
Property Insights of 1-Naphthol
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Naphthol. With a topological polar surface area (TPSA) of 20.2 Ų, 1-Naphthol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Naphthol has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Naphthol?
The CAS number of 1-Naphthol is 90-15-3.
What is the molecular formula of 1-Naphthol?
The molecular formula of 1-Naphthol is C10H8O.
What is the molecular weight of 1-Naphthol?
The molecular weight of 1-Naphthol is 144.05751 g/mol.
What are the applications of 1-Naphthol?
1-Naphthol is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Product profile: commercial lots are supplied at ≥99%....
Where can I buy 1-Naphthol?
You can request a quote for 1-Naphthol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Naphthol?
Yes, CoreyChem provides custom synthesis services for 1-Naphthol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.