(R)-1-Boc-3-hydroxypiperidine
TL;DR: (R)-1-Boc-3-hydroxypiperidine (CAS 94790-37-1) is a chemical compound with molecular formula C10H19NO3 and molecular weight 201.13649 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate
Also Known As: (R)-1-Boc-3-hydroxypiperidine, (R)-tert-Butyl 3-hydroxypiperidine-1-carboxylate, tert-butyl (3R)-3-hydroxypiperidine-1-carboxylate, Peridine Impurity 2, (R)-1-N-Boc-3-hydroxypiperidine
Technical Specifications
| Molecular Formula | C10H19NO3 |
| Molecular Weight | 201.13649 g/mol |
| XLogP | 1.3782 |
| Topological Polar Surface Area (TPSA) | 46.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 3 |
| Exact Mass | 201.13649 Da |
| Heavy Atoms | 14 |
| Complexity | 350.0 |
| Appearance | solid |
| Purity | ≥98.0% (T) |
| Melting Point | 200.0 |
| Solubility | acetonitrile: 0.1 g/mL, clear |
| SMILES | CC(C)(C)OC(=O)N1CCC[C@H](C1)O |
| InChIKey | UQYZFNUUOSSNKT-UHFFFAOYSA-N |
Product Description
Applications: Application Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high yields. HBTU is a peptide coupling agent for peptide synthesis. It has also been used in standard Fmoc-based solid-phase peptide synthesis (SPPS) protocol. Compare Similar Items View Full Comparison Show D
Chemical Property Profile of (R)-1-Boc-3-hydroxypiperidine
Property Insights of (R)-1-Boc-3-hydroxypiperidine
The XLogP value of 1.3782 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (R)-1-Boc-3-hydroxypiperidine. With a topological polar surface area (TPSA) of 46.2 Ų, (R)-1-Boc-3-hydroxypiperidine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (R)-1-Boc-3-hydroxypiperidine has 0 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (R)-1-Boc-3-hydroxypiperidine?
The CAS number of (R)-1-Boc-3-hydroxypiperidine is 94790-37-1.
What is the molecular formula of (R)-1-Boc-3-hydroxypiperidine?
The molecular formula of (R)-1-Boc-3-hydroxypiperidine is C10H19NO3.
What is the molecular weight of (R)-1-Boc-3-hydroxypiperidine?
The molecular weight of (R)-1-Boc-3-hydroxypiperidine is 201.13649 g/mol.
What does (R)-1-Boc-3-hydroxypiperidine look like?
(R)-1-Boc-3-hydroxypiperidine appears as solid.
What are the applications of (R)-1-Boc-3-hydroxypiperidine?
Application Recent studies show that crystal as well as solution structure of this coupling agent is a guanidinium N-oxide and not an uronium compound; Coupling reagent for peptide synthesis; advantages are: very low racemization, simple reaction conditions, very short reaction time, and high...
How should (R)-1-Boc-3-hydroxypiperidine be stored?
(R)-1-Boc-3-hydroxypiperidine should be stored 2-8°C.
Where can I buy (R)-1-Boc-3-hydroxypiperidine?
You can request a quote for (R)-1-Boc-3-hydroxypiperidine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (R)-1-Boc-3-hydroxypiperidine?
Yes, CoreyChem provides custom synthesis services for (R)-1-Boc-3-hydroxypiperidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.
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