p-Aminoacetophenone
TL;DR: p-Aminoacetophenone (CAS 99-92-3) is a chemical compound with molecular formula C8H9NO and molecular weight 135.06842 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(4-aminophenyl)ethanone
Also Known As: 4'-Aminoacetophenone, 4-Aminoacetophenone, 1-(4-Aminophenyl)ethanone, p-Aminoacetophenone, p-Acetylaniline
Application Areas
Top 5 of 21 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H9NO |
| Molecular Weight | 135.06842 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 43.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 135.06842 Da |
| Heavy Atoms | 10 |
| Complexity | 125.0 |
| Melting Point | 106 °C |
| Boiling Point | 294 °C; 195 °C at 15 mm Hg |
| Vapor Pressure | 0.00989 [mmHg] |
| Solubility | Soluble in hydrochloric acid |
| SMILES | CC(=O)C1=CC=C(C=C1)N |
| InChIKey | GPRYKVSEZCQIHD-UHFFFAOYSA-N |
Product Description
Applications: p-Aminoacetophenone is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
p-Aminoacetophenone (CAS 99-92-3) is a heterocyclic building block with the molecular formula C8H9NO and a molecular weight of 135.07 g/mol. Key physical properties include a solubility: Soluble in hydrochloric acid. Synonyms include 4'-Aminoacetophenone and 4-Aminoacetophenone.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of p-Aminoacetophenone
Property Insights of p-Aminoacetophenone
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for p-Aminoacetophenone. With a topological polar surface area (TPSA) of 43.1 Ų, p-Aminoacetophenone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, p-Aminoacetophenone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of p-Aminoacetophenone?
The CAS number of p-Aminoacetophenone is 99-92-3.
What is the molecular formula of p-Aminoacetophenone?
The molecular formula of p-Aminoacetophenone is C8H9NO.
What is the molecular weight of p-Aminoacetophenone?
The molecular weight of p-Aminoacetophenone is 135.06842 g/mol.
What are the applications of p-Aminoacetophenone?
p-Aminoacetophenone is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and...
Where can I buy p-Aminoacetophenone?
You can request a quote for p-Aminoacetophenone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for p-Aminoacetophenone?
Yes, CoreyChem provides custom synthesis services for p-Aminoacetophenone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.